W Noble

Latest

• Capturing cell type-specific chromatin structural patterns by applying topic modeling to single-cell Hi-C data
• Jointly embedding multiple single-cell omics measurements
• Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA binding proteins required for mitotic progression
• Unsupervised embedding of single-cell Hi-C data
• Comprehensive statistical inference of the clonal structure of cancer from multiple biopsies